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Ca/c2*1-22(2)32-31(34(41)36-26-12-8-5-9-13-26)30(23-10-6-4-7-11-23)33(24-14-16-25(35)17-15-24)37(32)19-18-27(38)20-28(42-3)21-29(39)40
InChiKey: QZJHREOKMZFHTH-DRRXZNNHSA-N
Oral dosing of INCB28060 results in time- and dose-dependent inhibition of c-MET phosphorylation and tumor growth in c-MET-driven mouse tumor models
In competitive experiments using membranes prepared from Chinese hamster ovary cells expressing the bradykinin receptor subtypes
It also induces spatial memory deficits in non-human primates expressing hM4Di in the prefrontal cortex
KHK-IN-1 hydrochloride astragaloside I Ca/c2*1-22(2)32-31(34(41)36-26-12-8-5-9-13-26)30(23-10-6-4-7-11-23)33(24-14-16-25(35)17-15-24)37(32)19-18-27(38)20-28(42-3)21-29(39)40KHK IN 1 hydrochloride is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp 27B in the ATP binding region of KHK. Product information CAS Number: 1303470 48 5 Molecular Weight: 459. 01 Formula: C21H27ClN8S Chemical Name: N8 (cyclopropylmethyl) N4 [2 (methylsulfanyl)phenyl] 2 (piperazin 1 yl) [1,3]diazino[5,4 d]pyrimidine 4,8 diamine hydrochloride Smiles: Cl. CSC1=CC=CC=C1NC1=NC(=NC2C1=NC=NC=2NCC1CC1)N1CCNCC1 InChiKey:
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