Fipronil 19483 Smiles: CC(C)(C)OC(=O)COCCOCCOCCOCC(O)=O

Smiles: CC(C)(C)OC(=O)COCCOCCOCCOCC(O)=O

Ro 15-2041 selectively inhibits cAMP-phosphodiesterase activity of a bovine calmodulin-independent but not of a calmodulin-dependent enzyme preparation

2-dimethylbutanoic acid

[O-]C(=O)C1NC2=CC(Cl)=CC(Cl)=C2C=1/C=C\C(=O)NC1C=CC=CC=1

1-3H3/b12-11+

Fipronil 19483 Smiles: CC(C)(C)OC(=O)COCCOCCOCCOCC(O)=OFipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non desensitizing glutamate induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1 2, CYP2B1 2, and CYP3A1 2 in isolated rat liver microsomes.